Education
Ph.D. in Medicinal Chemistry, The University of KansasDissertation: Photoredox-mediated Incorporation of Unnatural Amino Acids and the Development of a HIV-1 Packaging Inhibitor
B.S. in Chemistry, Southwest Baptist University
Selected Publications
Immel, J. R.; Chen, P.-H.; McDonald, P.; Roy, A.; Johnson, D.; Bloom, S. A Priori Design, Combinatorial Synthesis, and Assessment of an Antipackaging Peptide Against Human Immunodeficiency Virus 1: Functional Role of Unnatural Trp Mimetics and Serendipitous Discovery of a Protease Inhibitor. ChemMedChem 2026, 21 (13), e70372. https://doi.org/10.1002/cmdc.70372.Immel, J. R.; Alghafli, B. M.; Rodríguez Ugalde, A. A.; Bloom, S. Aqueous Flavin Photoredox Catalysis Drives Exclusive C3-Alkylation of Indolyl Radical Cations in Route to Unnatural Tryptophan Mimetics. Org. Lett. 2023, 25 (20), 3818–3822. https://doi.org/10.1021/acs.orglett.3c01398.
Immel, J. R; Bloom, S. carba-Nucleopeptides (cNPs): A Biopharmaceutical Modality Formed through Aqueous Rhodamine B Photoredox Catalysis. Angew. Chem.Int. Ed. 2022, e202205606. https://doi.org/10.1002/ange.202205606
Chilamari, M.; Immel, J. R; Chen, P.; Alghafli, B.; Bloom, S. Flavin Metallaphotoredox Catalysis: Synergistic Synthesis in Water.
ACS Catal. 2022, 12, 4175-4181. https://doi.org/10.1021/acscatal.2c00773
Immel, J. R; Chilamari, M..; Bloom, S. Combining Flavin Photocatalysis with Parallel Synthesis: A General Platform to Optimize Peptides with Non-Proteinogenic Amino Acids. Chem. Sci. 2021, 12, 10083. https://doi.org/10.1039/d1sc02562g
Professional Organizations
American Chemistry SocietySigma Zeta - Math and Science National Honor Society